+7 (495)150-11-22; 
+7 (484)399-31-30; 
+7 (499)110-40-67; Research and development topics
FSBI “NMIC of Radiology” of the Ministry of Health of the Russian Federation
| 1 | DEVELOPMENT OF NEW ORIGINAL HIGHLY EFFECTIVE ANTICANCER DRUGS BASED ON SEMI-SYNTHETIC HETEROCYCLIC COMPOUNDS – ANALOGUES OF COMBRETASTATIN AND PODOPHYLLOTOXIN AND BENZOTHIOPHENE DERIVATIVES |
| 2 | ASSESSMENT OF THE CLINICAL SIGNIFICANCE OF DETERMINING THE CONCENTRATION OF KIM-1 (KIDNEY INJURY MOLECULE) IN THE URINE OF RENAL CELL CARCINOMA |
| 3 | Minimally invasive treatment of oncourological diseases: focal permanent interstitial radiation therapy of prostate cancer with iodine-125 sources. |
| 4 | EXPERIMENTAL DEVELOPMENT AND CLINICAL APPROBATION OF APPROACHES AND SCHEMES FOR IMMUNE AND CELL THERAPY IN THE COMBINED TREATMENT OF ONCOLOGICAL DISEASES |
| 5 | Improvement of methods of combined and complex treatment of patients with malignant neoplasms based on the development of new high-tech methods of surgical treatment |
| 6 | SEARCH FOR OPTIMAL DOSE-VOLUME PARAMETERS OF IRRADIATION IN HIGH-DOSE RADIATION AND CHEMORADIOTHERAPY OF PRIMARY, RECURRENT AND METASTATIC MALIGNANT NEOPLASMS |
| 7 | Strategies of urological rehabilitation of patients with impaired function of the lower urinary tract after surgical interventions on the pelvic organs, treatment for oncological and neurological diseases on the basis of a comprehensive neurological examination |
| 8 | DEVELOPMENT AND CLINICAL EVALUATION OF THE EFFECTIVENESS OF NEW METHODS OF COMBINED (RADIATION, DRUG AND SURGICAL) TREATMENT OF TUMORS OF VARIOUS LOCALIZATIONS |
| 9 | DEVELOPMENT OF METHODS FOR ASSESSING AND PREDICTING HUMAN RADIATION RISKS FOR THE PURPOSES OF MONITORING THE HEALTH STATUS OF THE POPULATION OF THE RUSSIAN FEDERATION EXPOSED TO MAN-MADE SOURCES OF IONIZING RADIATION |
| 10 | Creation of methodological recommendations for the development of relevant tumor models in animals for the experimental study of various types of antitumor radiation therapy |
| 11 | Conducting preclinical studies of the safety and diagnostic efficiency of the developed RFLP based on a PSMA-specific ligand labeled with 99mTs radionuclide |
| 12 | Conducting preclinical studies of the safety and therapeutic efficacy of RFLP based on a conjugate of a somatostatin analog and labeled with a radioactive label (177Lu) for the treatment of inoperable NEOCODE (cipher) of a scientific topic assigned by the founder (organization) |
| 13 | Conducting safety and therapeutic efficacy studies of the developed radiopharmaceutical (RFLP) based on albumin microspheres 5-10 microns labeled 188Re for radiosynovectomy procedure in the local treatment of chronic inflammatory joint diseases |
| 14 | Conducting safety and therapeutic efficacy studies of the developed radiopharmaceutical (RFLP) based on albumin microspheres 20-40 microns labeled 188Re for intra-arterial radionuclide embolization procedure in the treatment of inoperable liver cancer |
| 15 | Conducting clinical trials of a radiopharmaceutical drug based on a prostate-specific ligand labeled with lutetium-177 (177Lu) radionuclide for radioligand therapy of metastatic castrate-resistant prostate cancer |
| 16 | DEVELOPMENT OF APPROACHES FOR THE CREATION OF PERSONALIZED COMPOSITE CONSTRUCTS CONTAINING ANTITUMOR DRUGS FOR THE TREATMENT OF BONE TISSUE LESIONS IN CANCER PATIENTS |
| 1 | Organizational and informational support of fundamental, applied scientific research and experimental developments |
| 2 | Improvement of methods of combined and complex treatment of patients with malignant neoplasms based on the development of new high-tech methods of surgical and drug treatment. |
| 3 | Development and optimization of high-tech methods of radiation therapy for tumors of the head and neck, female genital area and musculoskeletal system using the capabilities of modern radiotherapy technology and radio modification. |
| 4 | Creation of methodological recommendations for the development of relevant tumor models in animals for the experimental study of various types of antitumor radiation therapy |
| 5 | Development of new diagnostic approaches to early detection, staging and determination of optimal treatment tactics in patients with malignant neoplasms. |
| 6 | Changing the paradigm of radiation therapy of malignant neoplasms, individualization of approaches (treatment) based on new knowledge of clinical radiobiology, taking into account the possibilities of proton therapy. |
| 7 | To study the patterns and mechanisms of radiation and chemotherapeutic effects on normal and tumor cells as a basis for experimental development and clinical testing of means and methods of directed modification of effects. |
| 8 | Investigation of radiation risks of oncological and non-oncological morbidity (mortality) of a person under the influence of ionizing radiation. |
| 9 | Development of innovative approaches to the complex treatment of patients with malignant neoplasms, including neoadjuvant and adjuvant therapy (including new radiological technologies – brachytherapy, proton, chemoradiotherapy, photodynamic therapy) and radical surgical interventions (extended combined, organ-sparing, video-assisted, endoscopic, using microsurgical techniques), as well as a personalized approach based on predictive and prognostic factors. |
| 10 | Development of a method of photodynamic therapy of malignant neoplasms in independent and combined variants. |
| 11 | Development and implementation of new drugs, techniques and technologies of nuclear medicine to optimize the diagnosis and personalized radiotherapy of oncological diseases. |
| 12 | The study of methods of early diagnosis of chronic kidney disease and the development of methods to prevent its progression and negative effects on the central nervous system. |
| 13 | Prognostic criteria for the effectiveness of flap urethroplasty in various urethral strictures (including panstrictures) |
| 14 | Development of methods of intravesical therapy in the treatment of patients with various forms of chronic cystitis. |
| 15 | Sexual rehabilitation of oncological men. |
| 16 | Improvement of urological and oncourological care to the population of the Russian Federation based on the analysis of the main medical and statistical indicators. |
| 17 | Determination of the role of nutrition in the development of urolithiasis. |
