The NMIC of Radiology will show for the first time the use of a new domestic radiopharmaceutical with radionuclide rhenium-188

On March 10, the radionuclide treatment of chronic knee synovitis (radiosynovectomy) with the use of a radiopharmaceutical (RFLP) containing the radioisotope rhenium – 188 (188Re), developed and manufactured in Russia, Obninsk, will take place at the A.F. Tsyba MRSC – a branch of the FSBI NMIC Radiology of the Ministry of Health of the Russian Federation.

The event is significant in that this is the first procedure of its kind, which is performed using RFLP synthesized and manufactured in our country. This became possible thanks to the support of the Ministry of Health of Russia, which adopted a number of regulatory documents supporting Russian doctors and scientists in the development and clinical application of new radiopharmaceuticals.

Since 2000, radiosynovectomy with RFLP based on colloidal gold-198 has become unavailable in Russia due to the cessation of production of the domestic drug. Over the past few years, the NMIC of Radiology of the Ministry of Health of Russia has developed and, in cooperation with the FMBA of Russia, has passed preclinical tests of the radiopharmaceutical “MCA 5-10 microns, 188Re”, which is even more advanced than the colloidal gold –198 preparation, which makes the radiosynovetomy method demonstrated on March 10 extremely promising, both scientifically and and from a clinical point of view.

And developed jointly with JSC “SSC RF – FEI” (Obninsk) and the only compact rhenium generator in Russia-188 (model GREN-1), using which this RFLP is synthesized, makes it possible to replicate this method even in remote regions of our country.

The method is still being used within the framework of the Order of the Ministry of Health of Russia No. 1218n dated 20.12.2020, and after conducting clinical trials in 2021-2023, it will be registered with the Ministry of Health of Russia, and then a large number of centers will be able to provide such assistance to patients.

Press Service of the Federal State Budgetary Institution “NMIC of Radiology” of the Ministry of Health of Russia

Published 9 March 2022

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Contacts of the FSBI «NMMRC» of the Ministry of Health of the Russian Federation
Бесцветное здание МНИОИ им. П.А. Герцена в проекции
P. Hertsen Moscow Oncology Research Institute (MORI)

125284, Moscow, 2nd Botkinsky proezd, 3;
Polyclinic 119121, Moscow, ul. Pogodinskaya, 6, building. 1;
Call-center working hours: Mon-Fri 8:00 - 20:00,
+7(800)444-31-02 (Hot line),
+7(495)150-11-22 (Unified contact center), (Patient relations department), (Сhancellery), (Сhancellery).

Здание МРНЦ им. А.Ф. Цыба в проекции
A.Tsyb Medical Radiological Research Center (MRRC)

249036, Obninsk, Kaluga region, Koroleva str., 4.;
Call-center working hours: Mon-Fri. 8:00 - 20:00; Sat 08:00-18:00,
+7(800)250-87-00 (multichannel),

Бесцветное здание НИИ урологии и интервенционной радиологии им. Н.А. Лопаткина в проекции
N. Lopatkin Scientific Research Institute of Urology and Interventional Radiology (SRIUIR)

105425, Moscow, 3rd Parkovaya str., 51;
Call-center working hours: Mon-Fri. 8:00 - 20:00; Sat. 09:00-16:00, Sunday-day off,
+7(499)110-40-67 (Contact-center), (Information contact-center), (Сhancellery), (Сhancellery).

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